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Tyler Lastname's avatar

Does it work for stimulants?

jon's avatar

Could you ask Dr. Voliocelli to discuss the difference between addiction and dependence?

These terms often used interchangeably, but I understand dependence involves replacing an endogenous substance with an external one, while addiction refers more to a set of behaviors that may or may not include dependence.

For example, when someone takes opioids, their natural (endogenous) opioid system can go offline, leading to physical dependence and withdrawal when the external source is stopped — that’s classical dependence, which may or may not involve addictive behaviors.

Is that distinction accurate, and does Naltrexone work on addiction, dependence, or both? I realize I’m simplifying a complex topic, but I still think it’s one worth exploring and clarifying and more people understood. Thanks!

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